Tauseef, Mohammad
Ph.D., M.Pharm, RPh
Associate Professor with 1 year in rank
Biography
Mohammad Tauseef, MPharm, Ph.D., R.Ph., is a pharmacologist, biomedical researcher and licensed pharmacist with expertise in cardiovascular and pulmonary pharmacology. He earned his Ph.D. in pharmacology, specializing in cardiovascular pharmacology, from the University of Delhi in India. He received his Master of Pharmacy and Bachelor of Pharmacy from Hamdard University in New Delhi.
Tauseef completed postdoctoral training in the Department of Pharmacology and Regenerative Medicine at the University of Illinois College of Medicine in Chicago, where he later served as a research faculty member. His research focuses on molecular mechanisms regulating vascular endothelial barrier function, pulmonary inflammation, and acute lung injury.
His work investigates calcium signaling pathways, transient receptor potential channels, and sphingosine kinase signaling in vascular endothelial cells and their roles in cardiopulmonary disease. His research aims to identify signaling pathways that may serve as potential therapeutic targets for vascular inflammation and cardiopulmonary disorders.
Tauseef’s research has been supported by the National Heart, Lung, and Blood Institute and the American Heart Association. He has authored more than 25 peer-reviewed publications and scholarly book chapters in leading journals including Journal of Experimental Medicine, Cell Reports, Circulation Research, and FASEB Journal, contributing to the understanding of endothelial signaling mechanisms in vascular injury and inflammatory diseases.
In addition to his research activities, Tauseef has extensive experience in pharmacology education and mentoring. He served as assistant professor and later associate professor of pharmacology at Chicago State University, where he taught in the PharmD curriculum and supervised student research in cardiovascular pharmacology, endothelial biology and diabetes-associated vascular dysfunction.
He has received multiple teaching honors, including the Dean’s Award for Excellence in Teaching and several “Teacher of the Year” awards from PharmD students.
More about Mohammad Tauseef
Publications & Presentations
Anwar M, Balaji Raghunathrao VA, Amin R, Vellingiri V, Joshi JC, Akhter MZ, Tauseef M, El-Erian IH, Khaki N, Fancher IS, Abdelkarim H, Levitan I, Chronis K, Gaponenko V, Mehta D (2025). A Single Mutation in TRPC6 Protects Mice from Acute Lung Injury by Regenerating Endothelium. bioRxiv : the preprint server for biology.
Akhter MZ, Yazbeck P, Tauseef M, Anwar M, Hossen F, Datta S, Vellingiri V, Chandra Joshi J, Toth PT, Srivastava N, Lenzini S, Zhou G, Lee J, Jain MK, Shin JW, Mehta D (2024). FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity. Cell reports.
Imran M, Asdaq SMB, Khan SA, Unnikrishnan Meenakshi D, Alamri AS, Alsanie WF, Alhomrani M, Mohzari Y, Alrashed A, AlMotairi M, Alkhaldi EH, Alorabi AK, Alshrari AS, Tauseef M, Abida, Alaqel SI, Alam O, Bakht MA (2021). Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades. Pharmaceuticals (Basel, Switzerland).
Imran M, A S A, Tauseef M, Khan SA, Hudu SA, Abida (2021). Mucormycosis medications: a patent review. Expert opinion on therapeutic patents.
Joshi JC, Joshi B, Rochford I, Rayees S, Akhter MZ, Baweja S, Chava KR, Tauseef M, Abdelkarim H, Natarajan V, Gaponenko V, Mehta D (2020). SPHK2-Generated S1P in CD11b(+) Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages. Cell reports.
Srivastava N, Tauseef M, Amin R, Joshi B, Joshi JC, Kini V, Klomp J, Li W, Knezevic N, Barbera N, Siddiqui S, Obukhov A, Karginov A, Levitan I, Komarova Y, Mehta D (2020). Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Rayees S, Joshi JC, Tauseef M, Anwar M, Baweja S, Rochford I, Joshi B, Hollenberg MD, Reddy SP, Mehta D (2019). PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca(2+) Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation. Cell reports.
Siddiqui MR, Akhtar S, Shahid M, Tauseef M, McDonough K, Shanley TP (2019). miR-144-mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability. American journal of respiratory cell and molecular biology.
Shahid M, Hermes EL, Chandra D, Tauseef M, Siddiqui MR, Faridi MH, Wu MX (2018). Emerging Potential of Immediate Early Response Gene X-1 in Cardiovascular and Metabolic Diseases. Journal of the American Heart Association.
Syed H, Tauseef M, Ahmad Z (2018). A connection between antimicrobial properties of venom peptides and microbial ATP synthase. International journal of biological macromolecules.
Yazbeck P, Tauseef M, Kruse K, Amin MR, Sheikh R, Feske S, Komarova Y, Mehta D (2017). STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca(2+) Entry. Scientific reports.
Rajput C, Tauseef M, Farazuddin M, Yazbeck P, Amin MR, Avin Br V, Sharma T, Mehta D (2016). MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury. Arteriosclerosis, thrombosis, and vascular biology.
Tauseef M, Farazuddin M, Sukriti S, Rajput C, Meyer JO, Ramasamy SK, Mehta D (2016). Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX (2015). Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. American journal of respiratory cell and molecular biology.
Weber EW, Han F, Tauseef M, Birnbaumer L, Mehta D, Muller WA (2015). TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response. The Journal of experimental medicine.
Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX (2015). Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. American journal of physiology. Cell physiology.
Beckers CM, Knezevic N, Valent ET, Tauseef M, Krishnan R, Rajendran K, Hardin CC, Aman J, van Bezu J, Sweetnam P, van Hinsbergh VW, Mehta D, van Nieuw Amerongen GP (2015). ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension. Vascular pharmacology.
Sukriti S, Tauseef M, Yazbeck P, Mehta D (2014). Mechanisms regulating endothelial permeability. Pulmonary circulation.
Rizvi MR, Tauseef M, Shahid M, Babbar R, Fahim M, Sakhuja P, Sarin SK (2013). Nitric oxide and prostaglandin as mediators in the pathogenesis of hyperkinetic circulatory state in a model of endotoxemia-induced portal hypertension. Hepatology international.
Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D (2013). Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities. American journal of physiology. Lung cellular and molecular physiology.
Chava KR, Tauseef M, Sharma T, Mehta D (2012). Cyclic AMP response element-binding protein prevents endothelial permeability increase through transcriptional controlling p190RhoGAP expression. Blood.
Vandenbroucke St Amant E, Tauseef M, Vogel SM, Gao XP, Mehta D, Komarova YA, Malik AB (2012). PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity. Circulation research.
Tauseef M, Knezevic N, Chava KR, Smith M, Sukriti S, Gianaris N, Obukhov AG, Vogel SM, Schraufnagel DE, Dietrich A, Birnbaumer L, Malik AB, Mehta D (2012). TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. The Journal of experimental medicine.
Knezevic N, Tauseef M, Thennes T, Mehta D (2009). The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin. The Journal of experimental medicine.
Rahman Z, Kohli K, Zhang SQ, Khar RK, Ali M, Charoo NA, Tauseef M, Shamsher AA, Mohammed NN, Repka MA (2008). In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil. The Journal of pharmacy and pharmacology.
Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D (2008). Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circulation research.
Shahid M, Tauseef M, Sharma KK, Fahim M (2008). Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms. Experimental physiology.
Tauseef M, Shahid M, Sharma KK, Fahim M (2008). Antioxidative action of aspirin on endothelial function in hypercholesterolaemic rats. Basic & clinical pharmacology & toxicology.
Tauseef M, Sharma KK, Fahim M (2007). Aspirin restores normal baroreflex function in hypercholesterolemic rats by its antioxidative action. European journal of pharmacology.
Akhter MZ, Yazbeck P, Tauseef M, Anwar M, Hossen F, Datta S, Vellingiri V, Chandra Joshi J, Toth PT, Srivastava N, Lenzini S, Zhou G, Lee J, Jain MK, Shin JW, Mehta D (2024). FAK regulates tension transmission to the nucleus and endothelial transcriptome independent of kinase activity. Cell reports.
Imran M, Asdaq SMB, Khan SA, Unnikrishnan Meenakshi D, Alamri AS, Alsanie WF, Alhomrani M, Mohzari Y, Alrashed A, AlMotairi M, Alkhaldi EH, Alorabi AK, Alshrari AS, Tauseef M, Abida, Alaqel SI, Alam O, Bakht MA (2021). Innovations and Patent Trends in the Development of USFDA Approved Protein Kinase Inhibitors in the Last Two Decades. Pharmaceuticals (Basel, Switzerland).
Imran M, A S A, Tauseef M, Khan SA, Hudu SA, Abida (2021). Mucormycosis medications: a patent review. Expert opinion on therapeutic patents.
Joshi JC, Joshi B, Rochford I, Rayees S, Akhter MZ, Baweja S, Chava KR, Tauseef M, Abdelkarim H, Natarajan V, Gaponenko V, Mehta D (2020). SPHK2-Generated S1P in CD11b(+) Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages. Cell reports.
Srivastava N, Tauseef M, Amin R, Joshi B, Joshi JC, Kini V, Klomp J, Li W, Knezevic N, Barbera N, Siddiqui S, Obukhov A, Karginov A, Levitan I, Komarova Y, Mehta D (2020). Noncanonical function of long myosin light chain kinase in increasing ER-PM junctions and augmentation of SOCE. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Rayees S, Joshi JC, Tauseef M, Anwar M, Baweja S, Rochford I, Joshi B, Hollenberg MD, Reddy SP, Mehta D (2019). PAR2-Mediated cAMP Generation Suppresses TRPV4-Dependent Ca(2+) Signaling in Alveolar Macrophages to Resolve TLR4-Induced Inflammation. Cell reports.
Siddiqui MR, Akhtar S, Shahid M, Tauseef M, McDonough K, Shanley TP (2019). miR-144-mediated Inhibition of ROCK1 Protects against LPS-induced Lung Endothelial Hyperpermeability. American journal of respiratory cell and molecular biology.
Shahid M, Hermes EL, Chandra D, Tauseef M, Siddiqui MR, Faridi MH, Wu MX (2018). Emerging Potential of Immediate Early Response Gene X-1 in Cardiovascular and Metabolic Diseases. Journal of the American Heart Association.
Syed H, Tauseef M, Ahmad Z (2018). A connection between antimicrobial properties of venom peptides and microbial ATP synthase. International journal of biological macromolecules.
Yazbeck P, Tauseef M, Kruse K, Amin MR, Sheikh R, Feske S, Komarova Y, Mehta D (2017). STIM1 Phosphorylation at Y361 Recruits Orai1 to STIM1 Puncta and Induces Ca(2+) Entry. Scientific reports.
Rajput C, Tauseef M, Farazuddin M, Yazbeck P, Amin MR, Avin Br V, Sharma T, Mehta D (2016). MicroRNA-150 Suppression of Angiopoetin-2 Generation and Signaling Is Crucial for Resolving Vascular Injury. Arteriosclerosis, thrombosis, and vascular biology.
Tauseef M, Farazuddin M, Sukriti S, Rajput C, Meyer JO, Ramasamy SK, Mehta D (2016). Transient receptor potential channel 1 maintains adherens junction plasticity by suppressing sphingosine kinase 1 expression to induce endothelial hyperpermeability. FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
Smith KA, Voiriot G, Tang H, Fraidenburg DR, Song S, Yamamura H, Yamamura A, Guo Q, Wan J, Pohl NM, Tauseef M, Bodmer R, Ocorr K, Thistlethwaite PA, Haddad GG, Powell FL, Makino A, Mehta D, Yuan JX (2015). Notch Activation of Ca(2+) Signaling in the Development of Hypoxic Pulmonary Vasoconstriction and Pulmonary Hypertension. American journal of respiratory cell and molecular biology.
Weber EW, Han F, Tauseef M, Birnbaumer L, Mehta D, Muller WA (2015). TRPC6 is the endothelial calcium channel that regulates leukocyte transendothelial migration during the inflammatory response. The Journal of experimental medicine.
Fernandez RA, Wan J, Song S, Smith KA, Gu Y, Tauseef M, Tang H, Makino A, Mehta D, Yuan JX (2015). Upregulated expression of STIM2, TRPC6, and Orai2 contributes to the transition of pulmonary arterial smooth muscle cells from a contractile to proliferative phenotype. American journal of physiology. Cell physiology.
Beckers CM, Knezevic N, Valent ET, Tauseef M, Krishnan R, Rajendran K, Hardin CC, Aman J, van Bezu J, Sweetnam P, van Hinsbergh VW, Mehta D, van Nieuw Amerongen GP (2015). ROCK2 primes the endothelium for vascular hyperpermeability responses by raising baseline junctional tension. Vascular pharmacology.
Sukriti S, Tauseef M, Yazbeck P, Mehta D (2014). Mechanisms regulating endothelial permeability. Pulmonary circulation.
Rizvi MR, Tauseef M, Shahid M, Babbar R, Fahim M, Sakhuja P, Sarin SK (2013). Nitric oxide and prostaglandin as mediators in the pathogenesis of hyperkinetic circulatory state in a model of endotoxemia-induced portal hypertension. Hepatology international.
Schmidt TT, Tauseef M, Yue L, Bonini MG, Gothert J, Shen TL, Guan JL, Predescu S, Sadikot R, Mehta D (2013). Conditional deletion of FAK in mice endothelium disrupts lung vascular barrier function due to destabilization of RhoA and Rac1 activities. American journal of physiology. Lung cellular and molecular physiology.
Chava KR, Tauseef M, Sharma T, Mehta D (2012). Cyclic AMP response element-binding protein prevents endothelial permeability increase through transcriptional controlling p190RhoGAP expression. Blood.
Vandenbroucke St Amant E, Tauseef M, Vogel SM, Gao XP, Mehta D, Komarova YA, Malik AB (2012). PKCα activation of p120-catenin serine 879 phospho-switch disassembles VE-cadherin junctions and disrupts vascular integrity. Circulation research.
Tauseef M, Knezevic N, Chava KR, Smith M, Sukriti S, Gianaris N, Obukhov AG, Vogel SM, Schraufnagel DE, Dietrich A, Birnbaumer L, Malik AB, Mehta D (2012). TLR4 activation of TRPC6-dependent calcium signaling mediates endotoxin-induced lung vascular permeability and inflammation. The Journal of experimental medicine.
Knezevic N, Tauseef M, Thennes T, Mehta D (2009). The G protein betagamma subunit mediates reannealing of adherens junctions to reverse endothelial permeability increase by thrombin. The Journal of experimental medicine.
Rahman Z, Kohli K, Zhang SQ, Khar RK, Ali M, Charoo NA, Tauseef M, Shamsher AA, Mohammed NN, Repka MA (2008). In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil. The Journal of pharmacy and pharmacology.
Tauseef M, Kini V, Knezevic N, Brannan M, Ramchandaran R, Fyrst H, Saba J, Vogel SM, Malik AB, Mehta D (2008). Activation of sphingosine kinase-1 reverses the increase in lung vascular permeability through sphingosine-1-phosphate receptor signaling in endothelial cells. Circulation research.
Shahid M, Tauseef M, Sharma KK, Fahim M (2008). Brief femoral artery ischaemia provides protection against myocardial ischaemia-reperfusion injury in rats: the possible mechanisms. Experimental physiology.
Tauseef M, Shahid M, Sharma KK, Fahim M (2008). Antioxidative action of aspirin on endothelial function in hypercholesterolaemic rats. Basic & clinical pharmacology & toxicology.
Tauseef M, Sharma KK, Fahim M (2007). Aspirin restores normal baroreflex function in hypercholesterolemic rats by its antioxidative action. European journal of pharmacology.
Credentials, Certifications & Awards
Appointed as Associate Editor contributing to peer-review and editorial oversight in cell and developmental biology research.
Dean’s Award for Excellence in Teaching: Award recognizing outstanding teaching performance and contributions to pharmacy education.
Teacher of the Year Award – PharmD Class 2022; Student-selected award recognizing excellence in pharmacology teaching and mentorship.
Teacher of the Year Award – PharmD Class 2020: Student-selected teaching award for excellence in pharmacology education.
Travel Grant – Microcirculation in Acute Infections Symposium: Competitive travel award supporting participation in a scientific symposium focused on microcirculation and infectious diseases.
Young Scientist Travel Award: Competitive award recognizing promising early-career scientists and supporting presentation of research at Experimental Biology.
GATE Research Fellowship: Competitive national fellowship awarded based on Graduate Aptitude Test in Engineering performance for graduate research training.
Senior Research Fellowship: Prestigious fellowship supporting doctoral research in pharmacology and biomedical sciences.
Senior Research Fellowship: Competitive government fellowship supporting doctoral research in biomedical sciences.
Research Recognition Award: Award recognizing outstanding research presentation at the Experimental Biology conference.
Michael J. Bristow Postdoctoral Award: Poster competition award recognizing excellence in postdoctoral research.
Gold Medal Prize – Best Poster Presentation: First place award recognizing outstanding poster presentation at the College of Medicine Research Day.
Dean’s Award for Excellence in Teaching: Award recognizing outstanding teaching performance and contributions to pharmacy education.
Teacher of the Year Award – PharmD Class 2022; Student-selected award recognizing excellence in pharmacology teaching and mentorship.
Teacher of the Year Award – PharmD Class 2020: Student-selected teaching award for excellence in pharmacology education.
Travel Grant – Microcirculation in Acute Infections Symposium: Competitive travel award supporting participation in a scientific symposium focused on microcirculation and infectious diseases.
Young Scientist Travel Award: Competitive award recognizing promising early-career scientists and supporting presentation of research at Experimental Biology.
GATE Research Fellowship: Competitive national fellowship awarded based on Graduate Aptitude Test in Engineering performance for graduate research training.
Senior Research Fellowship: Prestigious fellowship supporting doctoral research in pharmacology and biomedical sciences.
Senior Research Fellowship: Competitive government fellowship supporting doctoral research in biomedical sciences.
Research Recognition Award: Award recognizing outstanding research presentation at the Experimental Biology conference.
Michael J. Bristow Postdoctoral Award: Poster competition award recognizing excellence in postdoctoral research.
Gold Medal Prize – Best Poster Presentation: First place award recognizing outstanding poster presentation at the College of Medicine Research Day.
Education
Ph.D., University of Delhi, New Delhi
MPharm, School of Pharmaceutical Education & Research, Hamdard University, New Delhi
BPharm, School of Pharmaceutical Education & Research, Hamdard University, New Delhi
MPharm, School of Pharmaceutical Education & Research, Hamdard University, New Delhi
BPharm, School of Pharmaceutical Education & Research, Hamdard University, New Delhi
Membership in Professional Organizations
Indian Pharmacological Society (Life Member)
The American Society for Pharmacology and Experimental Therapeutics (ASPET)
The American Society for Pharmacology and Experimental Therapeutics (ASPET)